What is cytokine storm? Does it cause secondary bacterial infection in the lungs or sepsis?


A ‘cytokine storm’ refers to the overproduction of inflammatory proteins. These inflammatory proteins are an important part of the immune response (the body’s response to infection). However, in a cytokine storm the overproduction of these proteins are harmful. Sepsis is defined as life threatening organ dysfunction caused by a dysregulated host response to infection. When we hear sepsis being talked about in the news, this is often referring to bacterial infection as the cause of sepsis. However, the cytokine storm that we see in COVID-19 can be thought of as a type of viral sepsis. In addition, it is possible that secondary bacterial infections may develop when the body’s immune system is weakened from fighting the viral infection.

Category: COVID-19